GRM2 anticorps (PE)
Aperçu rapide pour GRM2 anticorps (PE) (ABIN1430871)
Antigène
Voir toutes GRM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Rat (Rattus), Poulet, Chien, Boeuf (Vache)
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Purification
- purified by Protein A
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Immunogène
- KLH conjugated synthetic peptide derived from human GRM2/GLUR2
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Isotype
- IgG
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Indications d'application
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FCM(1:100-500)
Optimal working dilution should be determined by the investigator. -
Commentaires
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Excitation / Emission wavelength: 496nm / 578nm
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 µg/µL
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Buffer
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 4 °C for 12 months
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Date de péremption
- 12 months
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- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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Autre désignation
- Metabotropic Glutamate Receptor 2
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Sujet
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
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Poids moléculaire
- 96kDa
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ID gène
- 2912
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HGNC
- 0
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Pathways
- cAMP Metabolic Process, Dicarboxylic Acid Transport
Antigène
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